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Preheat the oven to 350 degrees and line a 12-cup muffin tin with paper liners. Set aside.
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Crust:
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Mix graham cracker crumbs and sugar together. Add in the melted butter and vanilla extract. Mix until combined.
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Add about 1-2 Tbsp of graham cracker crumbs in each muffin cup. Using the back of a Tbsp or your hands, press the crust into an even layer in each cup. (If you like a thick graham cracker crust, use about 2 Tbsp in each muffin cup. For a thinner crust, use 1 Tbsp.) Set aside.
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With a standing mixer or a hand mixer, beat cream cheese until fluffy and very smooth.
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Next, add in the sugar. Mix until fully incorporated, scraping down the sides of the bowl as needed.
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Next, add in the eggs one at a time, beating well after each addition.
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Lastly, add in vanilla extract. Mix until everything is combined and the cheesecake mixture is silky smooth (remember to scrape down the sides as needed).
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Divide the cheesecake batter evenly among the 12 muffin cups, filling each cup about 2/3 - 3/4 of the way full.
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Bake for 16-20 minutes, or until the edges of each cheesecake have set and the centers of each mini cheesecake jiggles slightly when the pan is gently moved.
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Turn off the oven, crack open the oven door, and let the cheesecakes slowly cool in the oven for 30-45 minutes (this helps prevent each cheesecake from cracking).
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Continue to let the cheesecakes cool to room temperature on the counter.
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Then, chill in the fridge at least 4 hours, or ideally overnight.
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Serve plain or topped with your choice of toppings.
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Keep leftovers in an airtight container in the refrigerator.